Potent repression of C-reactive protein (CRP) expression by the JAK1/2 inhibitor ruxolitinib in inflammatory human hepatocytes.
Identifieur interne : 000226 ( Main/Exploration ); précédent : 000225; suivant : 000227Potent repression of C-reactive protein (CRP) expression by the JAK1/2 inhibitor ruxolitinib in inflammatory human hepatocytes.
Auteurs : Marie Febvre-James [France] ; Valérie Lecureur [France] ; Olivier Fardel [France]Source :
- Inflammation research : official journal of the European Histamine Research Society ... [et al.] [ 1420-908X ] ; 2020.
English descriptors
Abstract
To determine whether inflammatory hepatocytes may constitute primary targets for ruxolitinib, a Janus kinase (JAK) inhibitor, its effects towards expression of hepatic acute-phase proteins, especially C-reactive protein (CRP), were assessed.
Url:
DOI: 10.1007/s00011-019-01293-1
PubMed: 31654094
Affiliations:
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Le document en format XML
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